Transcranial Magnetic Stimulation Optimized for Research
Brainsway® Deep Transcranial Magnetic Stimulation device includes a double blinding system for easily conducting randomized studies. Our Transcranial Magnetic Stimulation system features smart cards which are randomized between the patients. At the beginning of each treatment, the patient’s individual smart card is inserted into the card reader, automatically activating either the real coil or the sham coil, which are both located in the patient's head set. Both coils produce similar scalp sensations and acoustic artifact, so that neither the patient nor the caregiver knows whether the treatment taking place is real or sham.
Applicable for a Variety of Clinical & Neuroscience Studies
Brainsway Transcranial Magnetic Stimulation device can stimulate a wide variety of brain regions and networks. The Transcranial Magnetic Stimulation treatment can easily be applied to diverse clinical applications by designing coils targeting different locations, depths, directionalities & morphologies relevant to target neuronal structures, and usage of different protocols during treatment.
Brain regions which have been stimulated in various studies using Brainsway Transcranial Magnetic Stimulation device include:
- Lateral and medial prefrontal cortex (PFCׁׁ)
- Orbitofrontal cortex
- Right & left Insular cortex and entorhinal cortex
- Anterior cingulate cortex
- Posterior cingulate cortex
- Lateral and medial motor cortex, including deeper leg motor cortex
- Premotor cortex
- Supplementary motor cortex
- Right and left temporal cortex structures, including fusiform face area (FFA) & superior temporal sulcus (STS)
- Parietal cortex regions
- Occipital cortex regions
- Auditory cortex
- Visual cortex
Deep Stimulation – High Efficacy
Studies have shown that the depth and wide range of brain stimulation significantly and positively impact the results.
- “Many behavioral manifestations of neurological and psychiatric diseases are not solely the result of abnormality in one isolated brain region but represent alterations in brain networks and connectivity.” (Fox et al. Neurolmage 2012)
- "Deeper (ventral) PFC structures have significantly more connections with other reward system sites compared to superficial PFC". (Leh et al., 2007)
- Brainsway’s H-coil stimulation is deeper than that of Surface TMS coil. Therefore, it can stimulate tissues that have higher connectivity to the reward system.
- “There is significant inter-individual variability in the exact location of DLPFC sites having functional connectivity with subgenual cingulate “(Fox et al. Neuroimage 2012)
- “Effective response to standard TMS in MDD is strongly correlated with resting state functional connectivity between DLPFC stimulation sites and subgenual cingulate “(Fox et al. Biol. Psychiatry 2012)
- “Individualized targeting becomes less important with larger stimulation field sizes” (Fox et al. Biol. Psychiatry 2012)